The win rate alone does not determine the profitability of a trading strategy. It is entirely possible to have a profitable strategy with a low win rate or an unprofitable strategy with a high win rate. The risk-to-reward ratio plays a crucial role in determining the overall profitability and risk management of a trading strategy.

As you mentioned, a trading strategy with a high win rate often comes with a lower risk-to-reward ratio. This means that the potential reward per trade is smaller compared to the potential risk. While a high win rate can provide a psychological advantage and increase confidence, it may require a trader to achieve a high level of consistency to overcome trading costs and generate profits over the long term.

On the other hand, a trading strategy with a low win rate may have a higher risk-to-reward ratio. This means that the potential reward per trade is larger compared to the potential risk. While the lower win rate may result in a series of losing trades, the strategy can still be profitable if the average size of wins exceeds the average size of losses. However, it requires effective risk management and discipline to handle the emotional challenges associated with a lower win rate.

Ultimately, the selection of a trading strategy should consider various factors, including the win rate, risk-to-reward ratio, average size of wins and losses, trading costs, and the trader's risk tolerance and psychological makeup. Successful trading often involves finding a balance between these factors and aligning them with one's trading goals and preferences.